Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

GFP-Rab18 fluorescence co-localizes with ER/Golgi, dense granules or microneme markers. GFP-PfRab1A fluorescence is distinct from the localization of markers for the apicoplast (ACP), the ER (Bip), the Golgi (ERD2 and GRASP), as well as from staining of the ER/Golgi with Bodipy BFA.Morse D, Webster W, Kalanon M, Langsley G, McFadden GI. Plasmodium falciparum Rab1A Localizes to Rhoptries in Schizonts. PLoS One. 2016 11(6):e0158174

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GFP-PfRab1A fluorescence is found as discrete loci in living cells. A. GFP fluorescence is observed as discrete loci termed PfRab1Abodies in trophozoite and schizont stage parasites expressing GFP-PfRab1A. B. GFP-PfRab18 fluorescence is diffuse and closely associated with the nuclei. C-terminal HA-tagged PfRab1A is distributed equally throughout the parasite cytoplasm.Morse D, Webster W, Kalanon M, Langsley G, McFadden GI. Plasmodium falciparum Rab1A Localizes to Rhoptries in Schizonts. PLoS One. 2016 Jun 27;11(6):e0158174

See original on MMP

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