Species | Disruptability | Reference | Submitter | |
---|---|---|---|---|
P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM | |
P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
P. falciparum 3D7 |
Refractory |
32552779 Initial attempt to generate frameshift with CRISPR failed |
Theo Sanderson, Francis Crick Institute |
Species | Stage | Phenotype | Reference | Submitter |
---|---|---|---|---|
P. falciparum 3D7 | Asexual |
Attenuated |
32552779 (Knock down)
"The growth of more than 50% of the PfArp4-Ty1-Ribo parasites was arrested when the PfArp4 protein was downregulated". "Consistent with the results of the growth curve analysis, western blot (WB) analysis showed that the expression level of the PfArp4 protein was significantly reduced in the trophozoite stage parasites when GlcN was present in the culture (Fig. 1e). An abnormal morphology was also observed in the trophozoite-stage parasites of the PfArp4-Ty1-Ribo line treated with GlcN after one cell cycle". |
Theo Sanderson, Francis Crick Institute |
PlasmoDB | PVX_085340 |
GeneDB | PVX_085340 |
Malaria Metabolic Pathways | Localisation images Pathways mapped to |
Previous ID(s) | Pv085340 |
Orthologs | PBANKA_1020600 , PCHAS_1021400 , PF3D7_1422800 , PKNH_1335200 , PVP01_1326200 , PY17X_1022500 |
Google Scholar | Search for all mentions of this gene |