| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. falciparum 3D7 | Asexual |
Cell cycle arrest |
https://www.biorxiv.org/content/biorxiv/early/2019/04/17/406181.full.pdf
(Knock down)
'Detailed life cycle analysis revealed that inhibition of PfGRP170 results in parasite death in early schizogony. The protein is required for surviving a brief heat shock, suggesting that PfGRP170 is essential during febrile episodes in the host. We show that despite a predicted transit peptide, PfGRP170 is not essential for protein trafficking to the apicoplast.' |
Theo Sanderson, Google AI |
| PlasmoDB | PVX_083105 |
| GeneDB | PVX_083105 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | Pv083105 |
| Orthologs | PBANKA_1357200 , PCHAS_1361800 , PF3D7_1344200 , PKNH_1257200 , PVP01_1210600 , PY17X_1362900 |
| Google Scholar | Search for all mentions of this gene |