| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
RMgm-34 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
RMgm-4545 | Imported from RMgmDB | |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
RMgm-34 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
RMgm-4545 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-34 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-4545 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
No difference |
RMgm-34 | Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
No difference |
RMgm-34 | Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-34
Normal numbers of salivary gland sporozoites are produced. Sporozoites show a gliding motility similar to wild type sporozoites. Invasion of hepatocytes is significantly reduced (see phenotype 'liver stage'). |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-34
In vitro invasion of hepatocytes by the sporozoites is significantly reduced (35-38% reduction in number of completely intracellular sporozoites compared to wild type sporozoites). Invaded sporozoites develop normally inside HepG2 cells into mature liver schizonts.In vivo a 40-80% reduction in liver infection is observed after infection of C57BL/6 mice by intraveneous inoculation of sporozoites. |
Imported from RMgmDB |
| PlasmoDB | PVX_081560 |
| GeneDB | PVX_081560 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | Pv081560 |
| Orthologs | PBANKA_0209100 , PCHAS_0207500 , PF3D7_0104000 , PKNH_0209500 , PVP01_0210700 , PY17X_0210500 |
| Google Scholar | Search for all mentions of this gene |