Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-667 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-497 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-667 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-497 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-667
Gametocyte production was comparable to wild type parasites.Strongly reduced fertilisation. Evidence is presented that egress of both males and female gametes from the erythrocyte is affected
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-667
Strongly reduced fertilisation and production of ookinetes.Evidence is presented that egress of both males and female gametes from the erythrocyte is affected
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-667
Strongly reduced oocyst formation (94-98%)
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-667
The low numbers of oocysts produce normal numbers of sporozoites that are able to invade salivary glands. Sporozoites showed normal gliding motility and cell invasion capacity. Infectivity of sporozoites is reduced (see 'Additional remarks phenotype).
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-667
The low numbers of oocysts produce normal numbers of sporozoites that are able to invade salivary glands. Sporozoites showed normal gliding motility and cell invasion capacity. Infectivity of sporozoites is reduced (see 'Additional remarks phenotype').
Imported from RMgmDB

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