Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-1354 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Difference from wild-type
RMgm-1354
(Slightly) reduced growth rate of blood stages in mice
Imported from RMgmDB
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
No difference
RMgm-1354 Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-1354
Reduced ookinete production (33%)
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-1354
Reduced ookinete production (33%); Reduced oocyst production (61%)
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-1354
Reduced oocyst production (61%); Reduced sporozoite production (69%)
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-1354
Prolonged prepatent period after injecting mice intravenously with isolated sporozoites (8 days compared to 6 days of wild type sporozoites)
Imported from RMgmDB

More information