Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7 Asexual
No difference
32815516 (Conditional)
Conditional system in which mutant was generated with supplementation so that apicoplast is not required. "Surprisingly, we found that the apicoplast appeared to be unaffected by the deletion of TPI. We were able to amplify the sufB gene using PCR, indicating that the apicoplast genome had been maintained after TPI deletion"
Theo Sanderson, Francis Crick Institute

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