Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-486 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-4923 Imported from RMgmDB
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-486 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-4923 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-4923
Normal numbers of mature male and female gametocytes are produced. Pb22-KO male gametocytes showed a ~89% reduction in the exflagellation centers formed. Normal formation (and egress) of female gametes.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-4923
Strongly reduced ookinete formation
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4923
No oocyst formation
Imported from RMgmDB

More information