Cytosolic localization of GDHa D10 parasites were transfected with pHH1-gdha-GFP and WR99210-resistant parasites were analysed by fluorescence microscopy. GDHa-GFP (panel 1) does not co-localize with the nucleus (Hoechst 33342 staining, panel 2) nor with the mitochondrion (MitoTracker staining, panel 3). From the merged image it is clear that GDHa is a cytosolic protein.Storm J, Perner J, Aparicio I, Patzewitz EM, Olszewski K, Llinas M, Engel PC, Muller S. Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development. Malar J. 2011 Jul 14;10(1):193.

Localization of PfGDHs via GFP-fusion proteins. The data demonstrate that PfGDH1 and PfGDH3 are cytosolic proteins, whereas PfGDH2 is located in the apicoplast as demonstrated by colocalization with the acyl carrier protein (ACP).Zocher K, Fritz-Wolf K, Kehr S, Fischer M, Rahlfs S, Becker K. Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2. Mol Biochem Parasitol. 2012 183(1):52-62