| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
RMgm-1367 | Imported from RMgmDB | |
| P. berghei ANKA |
Refractory |
RMgm-4347 | Imported from RMgmDB | |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. falciparum 3D7 |
Possible |
35404116 \"For PfZIP1-TGD, the correct integration of the plasmid into the genomic locus and absence of wild-type locus were verified by PCR, and subsequent growth experiments revealed no growth defect compared to P. falciparum 3D7 wild-type parasites (Fig. S2B), suggesting its redundancy during asexual parasite proliferation. \" |
Theo Sanderson, Francis Crick Institute | |
| P. yoelii yoelii 17X |
Refractory |
RMgm-4809 | Imported from RMgmDB | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
Difference from wild-type |
RMgm-1367
Reduced parasite multiplication rate (PMR): 68% |
Imported from RMgmDB |
| P. berghei ANKA | Asexual |
Attenuated |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. falciparum 3D7 | Asexual |
No difference |
35404116 \"For PfZIP1-TGD, the correct integration of the plasmid into the genomic locus and absence of wild-type locus were verified by PCR, and subsequent growth experiments revealed no growth defect compared to P. falciparum 3D7 wild-type parasites (Fig. S2B), suggesting its redundancy during asexual parasite proliferation. \" |
Theo Sanderson, Francis Crick Institute |
| P. berghei ANKA | Gametocyte |
Difference from wild-type |
RMgm-1367
Strongly reduced female GCT numbers, male GCTs nearly undetectable, no exflagellation |
Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-1367
No ookinetes in vitro |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-1367
No oocysts in vivo |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-1367
No sporozoites in vivo |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-1367
No transmission by bite of infected mosquitoes |
Imported from RMgmDB |
| PlasmoDB | PKNH_1141100 |
| GeneDB | PKNH_1141100 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PK6_0750c, PKH_114010 |
| Orthologs | PBANKA_0107700 , PCHAS_0108300 , PF3D7_0609100 , PVP01_1139800 , PVX_113615 , PY17X_0109300 |
| Google Scholar | Search for all mentions of this gene |