Reduced growth of liver stages (At 24 hpi, HCS1 parasites were 3 m2 smaller, at 48h 53 m2, at 56h 73 m2 smaller than WT controls). Reduced merozoite/merosome formation.A delay of 2.1 days of the prepatent period after infecting mice with 5.000 sporozoites. Reduced infectivity of merozoites/merosomes produces as measured by blood infections in mice infected with merozoites/merosomes