| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. falciparum 3D7 | Asexual |
Attenuated |
30581113 (Conditional)
\"Here, we identify P. falciparum VPS45 as an essential factor in HCCU. Conditional inactivation of PfVPS45 led to an accumulation of host cell cytosol-filled vesicles within the parasite and inhibited the delivery of hemoglobin to the parasite\'s digestive vacuole, resulting in arrested parasite growth. \" |
Theo Sanderson, Francis Crick Institute |
| PlasmoDB | PKNH_0404500 |
| GeneDB | PKNH_0404500 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PK2_1500w, PKH_040370 |
| Orthologs | PBANKA_0313100 , PCHAS_0315200 , PF3D7_0216400 , PVP01_0408600 , PVX_002720 , PY17X_0313600 |
| Google Scholar | Search for all mentions of this gene |