PF3D7_1430700 NADP-specific glutamate dehydrogenase (GDH2)
Disruptability [+]
| Species | Disruptability | Reference | Submitter |
|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen |
Mutant phenotypes [+]
None reported yet. Please press the '+' button above to add one.Imaging data (from Malaria Metabolic Pathways)
Localization of PfGDHs via GFP-fusion proteins. The data demonstrate that PfGDH1 and PfGDH3 are cytosolic proteins, whereas PfGDH2 is located in the apicoplast as demonstrated by colocalization with the acyl carrier protein (ACP).Zocher K, Fritz-Wolf K, Kehr S, Fischer M, Rahlfs S, Becker K. Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2. Mol Biochem Parasitol. 2012 183(1):52-62
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| PlasmoDB | PF3D7_1430700 |
| GeneDB | PF3D7_1430700 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF14_0286 |
| Orthologs | PBANKA_1014000 , PBANKA_1026200 , PCHAS_1014800 , PCHAS_1027000 , PKNH_1328000 , PVP01_1318700 , PVP01_1332400 , PVX_085005 , PVX_085625 , PY17X_1015500 , PY17X_1015600 , PY17X_1028600 |
| Google Scholar | Search for all mentions of this gene |