PF3D7_1416800 lysine--tRNA ligase, putative
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM | |
Mutant phenotypes [+]
None reported yet. Please press the '+' button above to add one.Imaging data (from Malaria Metabolic Pathways)
Characterization of the lysylation system in P. falciparum. Immunofluorescence assays of infected red blood cells (iRBCs) containing PfKRS-2leader-GFP-transfected P. falciparum parasites. The GFP-tagged sequence colocalizes with ACP and not with Mitotracker, indicating that it is being specifically targeted to the apicoplast, consistently with the bioinformatic predictions. Hoen R, Novoa EM, López A, Camacho N, Cubells L, Vieira P, Santos M, Marin-Garcia P, Bautista JM, Cortés A, Ribas de Pouplana L, Royo M. Selective inhibition of an apicoplastic aminoacyl-tRNA synthetase from Plasmodium falciparum. Chembiochem. 2013 14(4):499-509.
See original on MMPMore information
| PlasmoDB | PF3D7_1416800 |
| GeneDB | PF3D7_1416800 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF14_0166 |
| Orthologs | PBANKA_1025900 , PCHAS_1026700 , PKNH_1341300 , PVP01_1332100 , PVX_085610 , PY17X_1028300 |
| Google Scholar | Search for all mentions of this gene |