Last updated 9 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
15184503 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
15184503 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-114 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-113 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Sporozoite
Attenuated
15184503 Theo Sanderson, Wellcome Trust Sanger Institute
P. berghei ANKA Asexual
No difference
RMgm-114 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-113 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-114 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-113 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-114 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-113 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-114
Normal numbers of oocysts are formed. Highly reduced formation of sporozoites within the oocysts. Only a few oocysts were observed that contained sporozoites.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-113
Normal numbers of oocysts are formed. Mutant oocysts did not produce any sporozoites. Analysis of the nuclear organization of the mutant oocysts by DNA staining showed similar developmental progression to that in wild-type oocysts. No evidence was found of cytokinesis and subsequent sporozoite formation.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-114
Highly reduced formation of sporozoites within the oocysts. Only a few oocysts were observed that contained sporozoites. No sporozoites were detected in salivary glands.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-113
No sporozoites are formed within the oocysts.
Imported from RMgmDB
P. berghei ANKA Liver
No difference
RMgm-114 Imported from RMgmDB
P. berghei ANKA Liver
No difference
RMgm-113 Imported from RMgmDB

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