Last updated 7 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Attenuated
29141210 (Conditional)
DDD tag led to delayed death on withdrawal of ligand. No effect seen with glmS ribozyme. Apicoplast lost integrity in aberrant cells. Chemical rescue by addition of IPP was possible indicating an apicoplast phenotype.
Theo Sanderson, Wellcome Trust Sanger Institute

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