Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Possible
RMgm-321 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-321 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-321 Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-321
Normal numbers of gametocytes, gametes and ookinetes are produced. Ookinetes can invade the midgut epithelium but the transition into the oocyst stage is severely affected. Ookinetes show a reduced DNA content, microneme defects and altered transcription profiles of genes (see 'Additional information').
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-321
Oocyst production is severely reduced and oocysts are small in size with much reduced and diffuse DNA staining compared to wild type.
Imported from RMgmDB

More information