Species | Disruptability | Reference | Submitter | |
---|---|---|---|---|
P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM |
Comparison of PfSec12 localization with markers for the ER and Golgi. Parasites were cotransfected with plasmids for expression of mRFP-PfSec12 (from the native pfsec12 5′ UTR) with either (A) GFP-SDEL, a marker for the general ER, or (B) PfGRASP-GFP, a cis-Golgi marker. mRFP-PfSec12 was localized throughout the ER coincident with GFP-SDEL, in close apposition to PfGRASP-labelled Golgi. Bar = 5 μm.Lee MC, Moura PA, Miller EA, Fidock DA. Plasmodium falciparum Sec24 marks transitional ER that exports a model cargo via a diacidic motif. Mol Microbiol. 2008 68(6):1535-46.
See original on MMPPlasmoDB | PF3D7_1322000 |
GeneDB | PF3D7_1322000 |
Malaria Metabolic Pathways | Localisation images Pathways mapped to |
Previous ID(s) | MAL13P1.121 |
Orthologs | PBANKA_1337400 , PCHAS_1342000 , PKNH_1206800 , PVP01_1232600 , PVX_116770 , PY17X_1342100 |
Google Scholar | Search for all mentions of this gene |