Last updated 7 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
RMgm-4093 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-4649 Imported from RMgmDB
P. yoelii yoelii 17X
Possible
RMgm-4385 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Gametocyte
Attenuated
23572579 (Insert. mut.) Theo Sanderson, Wellcome Trust Sanger Institute
P. berghei ANKA Asexual
No difference
RMgm-4649 Imported from RMgmDB
P. yoelii yoelii 17X Asexual
No difference
RMgm-4385 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-4649
Normal production of male gametocytes (and exflagellation). No production of mature female gametocytes. Evidence provided that immature female gametocytes are produced.
Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
Difference from wild-type
RMgm-4385
reduced numbers of male and female gametocytes
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-4649
Strongly reduced numbers of ookinetes in in vitro cultures. All ookinetes show aberrant morphology.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4649
No oocyst production
Imported from RMgmDB
P. yoelii yoelii 17X Oocyst
Difference from wild-type
RMgm-4385
reduced numbers of male and female gametocytes; reduced numbers of oocysts
Imported from RMgmDB
P. yoelii yoelii 17X Sporozoite
Difference from wild-type
RMgm-4385
reduced numbers of male and female gametocytes; reduced numbers of oocysts; reduced numbers of sporozoites
Imported from RMgmDB

More information

PlasmoDB PF3D7_1317200
GeneDB PF3D7_1317200
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) 1995.m00025, PF13_0097
Orthologs PBANKA_1415700 , PCHAS_1417500 , PKNH_1417900 , PVP01_1418100 , PVX_122680 , PY17X_1417400
Google Scholar Search for all mentions of this gene