PF3D7_1253000 gametocyte erythrocyte cytosolic protein (GECO)
Disruptability [+]
| Species | Disruptability | Reference | Submitter |
|---|---|---|---|
| P. falciparum 3D7 |
Possible |
18614010 | Theo Sanderson, Wellcome Trust Sanger Institute |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen |
| P. falciparum 3D7 |
Possible |
21965515 | Theo Sanderson, Francis Crick Institute |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. falciparum 3D7 | Asexual |
No difference |
21965515 | Theo Sanderson, Francis Crick Institute |
| P. falciparum 3D7 | Gametocyte |
Attenuated |
23572579 (Insert. mut.) | Theo Sanderson, Wellcome Trust Sanger Institute |
| P. falciparum 3D7 | Gametocyte |
No difference |
21965515 | Theo Sanderson, Francis Crick Institute |
Imaging data (from Malaria Metabolic Pathways)
Localization of PfGECO (HSP40) to the host RBC during gametocytogenesis. IFA was performed on wild type 3D7 gametocyte stages I-V using anti-PfGECO serum (red) with the nucleus stained with DAPI (4,6-diamidino-2-phenylindole; blue). Also shown are the bright field (BF) and merged images.Morahan BJ, Strobel C, Hasan U, Czesny B, Mantel PY, Marti M, Eksi S, Williamson KC. Functional analysis of the exported type IV HSP40 protein PfGECO in P. falciparum gametocytes. Eukaryot Cell. 2011 10(11):1492-503.
See original on MMP
PfGECO is external to Pfs16 and internal to MESA. Co-localization IFA was performed on gametocyte stages I-IV using anti-PfGECO serum (red) and either (A) anti-Pfs16 (green) serum or (B) anti-MESA (green) serum. Also shown is the parasite nucleus stained with DAPI (blue), the bright field (BF) and the merged images.Morahan BJ, Strobel C, Hasan U, Czesny B, Mantel PY, Marti M, Eksi S, Williamson KC. Functional analysis of the exported type IV HSP40 protein PfGECO in P. falciparum gametocytes. Eukaryot Cell. 2011 10(11):1492-503.
See original on MMPMore information
| PlasmoDB | PF3D7_1253000 |
| GeneDB | PF3D7_1253000 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | 2277.t00508, PF12_0010, PFL2550w |
| Orthologs | |
| Google Scholar | Search for all mentions of this gene |