| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. berghei ANKA |
Possible |
RMgm-4855 | Imported from RMgmDB | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Asexual |
No difference |
RMgm-4855 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-4855 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-4855
Normal numbers of gametocytes are produced. Whereas, pbqsox deletion did not affect the formation of macrogametes, it reduced the number of exflagellation centers by 28.0%. Ookinetes in the pbqsox line retained normal morphology, but the proportion of mature ookinetes (stage IV-VI) was reduced by 43.1%.Consistent with the in vitro ookinete conversion result, the number of ookinetes formed in the blood bolus of mosquitoes feeding on pbqsox-infected mice was 60.264.6% lower than that with the WT parasites. |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-4855
A 61.862.8% reduction in oocyst number/midgut in mosquitoes after feeding on pbqsox-infected mice as compared to those fed on WT parasite-infected mice. The gross morphology of oocysts appeared normal in the pbqsox parasites compared to the WT |
Imported from RMgmDB |
| PlasmoDB | PF3D7_1242000 |
| GeneDB | PF3D7_1242000 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | 2277.t00404, MAL12P1.402, PFL2020c |
| Orthologs | PBANKA_1455400 , PCHAS_1457700 , PKNH_1461300 , PVP01_1459100 , PVX_101000 , PY17X_1457900 |
| Google Scholar | Search for all mentions of this gene |