| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
RMgm-4145 | Imported from RMgmDB | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
Difference from wild-type |
RMgm-4145
Reduced growth/multiplication of asexual blood stages. |
Imported from RMgmDB |
| P. berghei ANKA | Asexual |
Attenuated |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Gametocyte |
Difference from wild-type |
RMgm-4145
Strongly reduced exflagellation (male gamete formation). Reduced DNA replication during male gamete formation (mainly blocked at 2N; proportions of haploid microgametocytes in 10 min activated microgametocytes were similar in the KO and its WT counterpart indicating that SOC2 is not required for initiation of DNA replication and DNA replication per se. However, 47% of the parasites remained diploid and 20% and 16% reached the 4N and 8N levels, respectively. Strongly reduced mitotoic spindle formation in microgametocytes at 10 min. after activation. Normal axoneme in microgametocytes at 10 min. after activation. |
Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-4145
Strongly reduced exflagellation (male gamete formation). Reduced DNA replication during male gamete formation (mainly blocked at 2N; proportions of haploid microgametocytes in 10 min activated microgametocytes were similar in the KO and its WT counterpart indicating that SOC2 is not required for initiation of DNA replication and DNA replication per se. However, 47% of the parasites remained diploid and 20% and 16% reached the 4N and 8N levels, respectively. Strongly reduced mitotoic spindle formation in microgametocytes at 10 min. after activation. Normal axoneme in microgametocytes at 10 min. after activation. |
Imported from RMgmDB |
| PlasmoDB | PF3D7_1227500 |
| GeneDB | PF3D7_1227500 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | 2277.t00266, MAL12P1.266, PFL1330c |
| Orthologs | PBANKA_1442200 , PCHAS_1444300 , PKNH_1446900 , PVP01_1445700 , PVX_124005 , PY17X_1444700 |
| Google Scholar | Search for all mentions of this gene |