| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. berghei ANKA |
Possible |
RMgm-5231 | Imported from RMgmDB | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Asexual |
No difference |
RMgm-5231 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-5231 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
No difference |
RMgm-5231 | Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-5231
A significant decrease (approx. 70%) in the number of oocysts at day 9 post-infection and oocysts at this stage of development were smaller in size. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-5231
Despite the overall smaller oocyst numbers and sizes in the PbLRR1KO lines, a substantial proportion of oocysts completed development to sporozoites and no significant effects on salivary gland colonization were observed. Sporozoites were infective in both in vitro hepatocyte cultures and in mice, albeit with a slightly longer prepatent period. |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-5231
Sporozoites were infective in both in vitro hepatocyte cultures and in mice, albeit with a slightly longer prepatent period. |
Imported from RMgmDB |
| PlasmoDB | PF3D7_1032800 |
| GeneDB | PF3D7_1032800 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF10_0320, PF10_0320a |
| Orthologs | PBANKA_0516600 , PCHAS_0516700 , PKNH_0617600 , PVP01_0617900 , PVX_111085 , PY17X_0517700 |
| Google Scholar | Search for all mentions of this gene |