PF3D7_1031000 25 kDa ookinete surface antigen precursor (Pfs25)
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
RMgm-2 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
RMgm-2 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-2 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-2
Slight inhibition of ookinete development (slight reduction in ookinete numbers in in vitro cultures); ookinetes do not form the typical clusters of multiple ookinetes in vitro |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-2
Slight inhibition of oocyst development (slight reduction in ookinete numbers in in Anopheles stephensi mosquitoes). |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
No difference |
RMgm-2 | Imported from RMgmDB |
| P. berghei ANKA | Liver |
No difference |
RMgm-2 | Imported from RMgmDB |
Imaging data (from Malaria Metabolic Pathways)
Immunofluorescence assays, using specific antibodies, detected the proteins of interest (in green) in asexual blood stage (ABS) parasites, using MSP1 (in red). Nuclei were highlighted by Hoechst nuclear stain (in blue). Bar, 5 μm. Ngwa CJ, Scheuermayer M, Mair GR, Kern S, Brügl T, Wirth CC, Aminake MN, Wiesner J, Fischer R, Vilcinskas A, Pradel G. Changes in the transcriptome of the malaria parasite Plasmodium falciparum during the initial phase of transmission from the human to the mosquito. BMC Genomics. 2013 Apr 15;14:256
See original on MMPMore information
| PlasmoDB | PF3D7_1031000 |
| GeneDB | PF3D7_1031000 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF10_0303 |
| Orthologs | PBANKA_0515000 , PCHAS_0515100 , PKNH_0615700 , PVP01_0616100 , PVX_111175 , PY17X_0516000 |
| Google Scholar | Search for all mentions of this gene |