PF3D7_1022800 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (GcpE)
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM | |
Mutant phenotypes [+]
None reported yet. Please press the '+' button above to add one.Imaging data (from Malaria Metabolic Pathways)
Expression and localization of Kae1api interaction partners. Representative IFA images from RFA-tagged parasites are shown. IspG (top row), EF-Ts (middle row), and a putative RNA helicase (bottom row) co-localize with an apicoplast marker (ACP) and not with mitochondria. Mitochondria and nuclei were visualized with Mitotracker and DAPI-DNA stain, respectively. IFAstudies confirmed the apicoplast localization of all three proteins.Mallari JP, Oksman A, Vaupel B, Goldberg DE. Kinase-Associated Endopeptidase 1 (Kae1) Participates in an Atypical ribosome-Aassociated complex in the apicoplast of Plasmodium falciparum. J Biol Chem. 2014 Sep 9 [Epub ahead of print]
See original on MMPMore information
| PlasmoDB | PF3D7_1022800 |
| GeneDB | PF3D7_1022800 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF10_0221 |
| Orthologs | PBANKA_0507000 , PCHAS_0507100 , PKNH_0607100 , PVP01_0608000 , PVX_111575 , PY17X_0508100 |
| Google Scholar | Search for all mentions of this gene |