Last updated 2 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
RMgm-4540 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Attenuated
https://www.biorxiv.org/content/10.1101/2020.02.13.947507v1.abstract (Knock down)
Late stage maturation affected. Haemoglobin motility reduced. Trolox rescues botth effects (to some extent)
Theo Sanderson, Francis Crick Institute
P. falciparum 3D7 Asexual
Attenuated
32601225 (Conditional)
modest merozoite invasion defect upon rupture of the PfPV5-null schizonts, reducing parasite replication
Abhinay Ramaprasad, The Francis Crick Institute

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