Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

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Imaging data (from Malaria Metabolic Pathways)

Nuclear localization of PfHDAC1; P. falciparum segmentors were treated with (A) preimmune serum and (B) anti-PfHDAC1428-445 peptide antiserum. The intraerythrocytic merozoites could be easily discernible from each other. N, nucleus; R, rhoptry; Hz, hemozoin. (Original magnification31 200)Joshi MB, Lin DT, Chiang PH, Goldman ND, Fujioka H, Aikawa M, Syin C. Molecular cloning and nuclear localization of a histone deacetylase homologue in Plasmodium falciparum. Mol Biochem Parasitol. 1999 99:11-9. Copyright Elsevier 2009.

See original on MMP

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