Normal ookinete production in vitro. Light microscope morphology of mature ookinetes normal. Nuclei of mutant ookintes were different from those of wild type ookinetes at the electron microscope level (see 'Additional information phenotype')

Normal ookinete production in vitro. Mutant parasites produced 50-80% less oocysts. Mutant oocysts were smaller compared to wild type oocysts (see also 'Additional information phenotype'). Mutant oocysts produced 30-fold lower midgut sporozoites.

Mutant parasites produced 50-80% less oocysts. Mutant oocysts were smaller compared to wild type oocysts. Mutant oocysts produced 30-fold lower midgut sporozoites and 20-fold lower numbers of salivary gland sporozoites (day 21 after infection). Mutant sporozoites are not infective to mice.

Mutant oocysts produced 30-fold lower midgut sporozoites and 20-fold lower numbers of salivary gland sporozoites (day 21 after infection). Mutant sporozoites are not infective to mice.