Last updated 3 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. falciparum 3D7
Refractory
22127061 Theo Sanderson, Wellcome Trust Sanger Institute
P. falciparum 3D7
Possible
18614010
Integration confirmed by Southern blot
Theo Sanderson, Francis Crick Institute [Thank you to Thorey Jonsdottir for pointing out an error I made in transcribing this phenotype previously]
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. berghei ANKA
Refractory
RMgm-551 Imported from RMgmDB
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

Immunoelectron micrography on streptolysin-O permeablised mature trophozoite (36 h after invasion of the merozoites) infected cells. FEST is associated with Golgi-like structures in the red cell cytoplasm (a and b); vesicles in the red cell cytoplasm (c); the parasite plasma membrane (d) and membranous structures in the red cell cytoplasm (e); knobs in the parasitised red cell plasma membrane (f–h). A cross-section through a parasitised red cell is shown in (i). FEST is associated with membranous structures in the red cell and with the red cell membrane, particularly at parasite-induced knobs.Kun JF, Hibbs AR, Saul A, McColl DJ, Coppel RL, Anders RF. A putative Plasmodium falciparum exported serine/threonine protein kinase. Mol Biochem Parasitol. 1997 85:41-51. Copyright Elsevier 2009.

See original on MMP

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