PF3D7_0606900 glutaredoxin-like protein (GLP2)
Disruptability [+]
| Species | Disruptability | Reference | Submitter |
|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
Attenuated |
PlasmoGEM (Barseq) | PlasmoGEM |
Imaging data (from Malaria Metabolic Pathways)
GFP targeting by various P. falciparum redox proteins of the glutathione system. (A) Cytosolic localization of GLP1. (B) Cytosolic localization of GLP2. (C) Dual localization (cytosol and apicoplast) of the tGloII N-terminus. (D) PV-localization of the signal peptide of GR (the parasites showed a fast bleaching fluorescence, leading to a high background signal). Live cell imaging of erythrocytes infected with transgenic parasites for solely cytosolic GFP signals. Colocalization of GFP and the apicoplast marker ACP in fixed, immunodecorated cells.Kehr S, Sturm N, Rahlfs S, Przyborski JM, Becker K. Compartmentation of redox metabolism in malaria parasites. PLoS Pathog. 2010 6:e1001242.
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| PlasmoDB | PF3D7_0606900 |
| GeneDB | PF3D7_0606900 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | 2270.t00247, MAL6P1.72, PFF0340c |
| Orthologs | PBANKA_0105500 , PCHAS_0106100 , PKNH_1143400 , PVP01_1142100 , PVX_113510 , PY17X_0107000 |
| Google Scholar | Search for all mentions of this gene |