PF3D7_0523000 multidrug resistance protein 1 (MDR1)
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
26991313 | Theo Sanderson, Wellcome Trust Sanger Institute | |
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Refractory |
RMgm-1158 | Imported from RMgmDB | |
| P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. yoelii yoelii 17X |
Refractory |
RMgm-4803 | Imported from RMgmDB | |
Mutant phenotypes [+]
None reported yet. Please press the '+' button above to add one.Imaging data (from Malaria Metabolic Pathways)
Immunogold EM localization of Pghl/PfMDR1. Asynchronous cultures of the cloned line ITG2F6 were analyzed by postembedding immunolabeling as described in Materials and Methods. The antibody used was the affinity-purified anti-Pghl followed by protein A conjugated to 10-nm gold particles. A trophozoite is shown on the left and a free digestive vacuole on the fight. Bars, 0.5 mm.Cowman AF, Karcz S, Galatis D, Culvenor JG. A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole. J Cell Biol. 1991 113:1033-42. PMID:
See original on MMPMore information
| PlasmoDB | PF3D7_0523000 |
| GeneDB | PF3D7_0523000 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | MAL5P1.230, PFE1150w |
| Orthologs | PBANKA_1237800 , PCHAS_1238200 , PKNH_1009900 , PVP01_1010900 , PVX_080100 , PY17X_1241000 |
| Google Scholar | Search for all mentions of this gene |