| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
RMgm-1355 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
RMgm-1301 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
RMgm-1355 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
RMgm-1301 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-1355 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-1301 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
No difference |
RMgm-1355 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-1301
The mutants developed into ookinetes with normal conversion rates and morphology. |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-1355
No significant reduction in the number of cyc3 oocysts compared to WT controls at 5 dpi. However a significant reduction was observed at 7 dpi, which became even more evident at 10, 14 and 21 dpi. cyc3 oocysts were substantially smaller than WT. The number of cyc3 sporozoites was significantly reduced compared to WT.Many (>60%) of the cyc3 oocysts showed no evidence of sporulation |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-1301
Strongly reduced oocyst production. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-1355
No significant reduction in the number of cyc3 oocysts compared to WT controls at 5 dpi. However a significant reduction was observed at 7 dpi, which became even more evident at 10, 14 and 21 dpi. cyc3 oocysts were substantially smaller than WT. The number of cyc3 sporozoites was significantly reduced compared to WT. Sporozoites, however, showed a normal infectivity to mice. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-1301
Strongly reduced (salivary gland) sporozoite production. |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-1355
The number of cyc3 sporozoites was significantly reduced compared to WT. Sporozoites, however, showed a normal infectivity to mice. |
Imported from RMgmDB |
| PlasmoDB | PF3D7_0518400 |
| GeneDB | PF3D7_0518400 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | MAL5P1.184, PFE0920c |
| Orthologs | PBANKA_1233200 , PCHAS_1233800 , PKNH_1014800 , PVP01_1015500 , PVX_080325 , PY17X_1236600 |
| Google Scholar | Search for all mentions of this gene |