PF3D7_0516600 sporozoite surface antigen MB2 (MB2)
Disruptability [+]
| Species | Disruptability | Reference | Submitter |
|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen |
Mutant phenotypes [+]
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
Attenuated |
PlasmoGEM (Barseq) | PlasmoGEM |
Imaging data (from Malaria Metabolic Pathways)
E is a cross-section of a trophozoite in an erythrocyte (E), showing localization principally to the parasite nucleus (N) and some in the parasite cytoplasm (Pc). F is a section of schizonts showing MB2 localization to the nucleus and some cytoplasm. Hemazoin (Hz) also is visible. Both E and F were reacted with anti-B domain antiserum. G shows sections of parasites at the merozoite (Mz) stage reacted with anti-A domain antiserum, showing only cytoplasmic localization.Nguyen TV, Fujioka H, Kang AS, Rogers WO, Fidock DA, James AA. Stage-dependent localization of a novel gene product of the malaria parasite, Plasmodium falciparum. J Biol Chem. 2001 276:26724-31.
See original on MMPMore information
| PlasmoDB | PF3D7_0516600 |
| GeneDB | PF3D7_0516600 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | MAL5P1.166, PFE0830c |
| Orthologs | PBANKA_1231400 , PCHAS_1232000 , PKNH_1016700 , PVP01_1017400 , PVX_080420 , PY17X_1234800 |
| Google Scholar | Search for all mentions of this gene |