PF3D7_0400400 erythrocyte membrane protein 1, PfEMP1 (VAR)
Disruptability [+]
| Species | Disruptability | Reference | Submitter |
|---|---|---|---|
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen |
Mutant phenotypes [+]
None reported yet. Please press the '+' button above to add one.Imaging data (from Malaria Metabolic Pathways)
Immunofluorescence assay with antisera to HB3var3 (1/100 dilution) showing punctate surface fluorescence on live infected erythrocytes typical of PfEMP1 antibodies. This groupA-like var genes was highly transcribed in three P. falciparum strains selected for adhesion to anHBEC line.Claessens A, Adams Y, Ghumra A, Lindergard G, Buchan CC, Andisi C, Bull PC, Mok S, Gupta AP, Wang CW, Turner L, Arman M, Raza A, Bozdech Z, Rowe JA. A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells. Proc Natl Acad Sci U S A. 2012 109(26):E1772-81.
See original on MMPMore information
| PlasmoDB | PF3D7_0400400 |
| GeneDB | PF3D7_0400400 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | MAL4P1.4, PFD0020c |
| Orthologs | |
| Google Scholar | Search for all mentions of this gene |