| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. berghei ANKA |
Possible |
RMgm-4688 | Imported from RMgmDB | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Asexual |
No difference |
RMgm-4688 | Imported from RMgmDB |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-4688 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-4688
Ookinete formation did not reveal a significant difference between mutant and WT parasite development with ookinete morphologies similar as revealed by Giemsa-stained smears and scanning electron microscopy analysis. Ookinetes were also formed in vivo as revealed by Giemsa stained smears of mosquito midguts formed 24 h after feeding on an infected mouse. Mature omd(-) ookinetes were completely devoid of productive motility; at most they displayed stretching of the ookinete.In vivo transmission experiments, where mosquitoes are allowed to blood feed on mice infected with the omd(-)cl1 mutant, did not result in the establishment of oocysts in three independent feedings; WT parasites on the other hand transmitted normally. |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-4688
In vivo transmission experiments, where mosquitoes are allowed to blood feed on mice infected with the omd(-)cl1 mutant, did not result in the establishment of oocysts in three independent feedings; WT parasites on the other hand transmitted normally. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-4688
No oocyst and sporozoite formation |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-4688
No oocyst and sporozoite formation. No transmission to mice by bite of infected mosquitoes. |
Imported from RMgmDB |
| PlasmoDB | PF3D7_0309100 |
| GeneDB | PF3D7_0309100 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PFC0381c |
| Orthologs | PBANKA_0407300 , PCHAS_0408200 , PKNH_0833600 , PVP01_0831100 , PVX_119570 , PY17X_0409700 |
| Google Scholar | Search for all mentions of this gene |