PF3D7_0213100 protein SIS1 (SIS1)
Disruptability [+]
| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
Mutant phenotypes [+]
None reported yet. Please press the '+' button above to add one.Imaging data (from Malaria Metabolic Pathways)
PFB0595w is localized to the parasite cytosol. (A) Immunolocalization of PFB0595w using the anti-PFB0595w antibody on fixed P. falciparum 3D7-infected erythrocytes stained with Hoechst 33258 (to visualize the nucleus) BF, bright field. (B) Localization of the GFP signal through live cell imaging of PFB0595w-GFP transfectants stained with Hoechst 33528. DIC, differential interference contrast; Merge, PFB0595w-GFP plus Hoechst 33258 channel; Overlay, DIC plus merge. (C) Indirect immunofluorescence localization of GFP and PfHsp70-1 in PFB0595w-GFP transfectants using the anti-PfHsp70-1 antibody. Merge, anti-PfHsp70-1 plus PFB0595w-GFP and Hoechst 33258;Overlay, DIC plus merge.Njunge JM, Mandal P, Przyborski JM, Boshoff A, Pesce ER, Blatch GL. PFB0595w is a Plasmodium falciparum J protein that co-localizes with PfHsp70-1 and can stimulate its in vitro ATP hydrolysis activity. Int J Biochem Cell Biol. 2015 62:47-53.
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| PlasmoDB | PF3D7_0213100 |
| GeneDB | PF3D7_0213100 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PF02_0123, PFB0595w |
| Orthologs | PBANKA_0310000 , PCHAS_0312100 , PKNH_0407900 , PVP01_0411800 , PVX_002875 , PY17X_0310500 |
| Google Scholar | Search for all mentions of this gene |