Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4331 Imported from RMgmDB
P. berghei ANKA
Refractory
RMgm-4994 Imported from RMgmDB
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. yoelii yoelii 17X
Refractory
RMgm-4802 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Difference from wild-type
RMgm-4331
Evidence is presented that the gene can be targeted for deletion indicating a non-essential role for blood stage growth/multiplication. However, see also RMgm-3980 for negative attempts to delete/disrupt this gene.
Imported from RMgmDB
P. falciparum 3D7 Asexual
Egress defect
33762339 (Conditional)
PfICM1-null schizonts exhibited an abnormal phenotype, with either complete loss of egress or rounding up with increased intracellular merozoite mobility
Abhinay Ramaprasad, The Francis Crick Institute

More information

PlasmoDB PCHAS_1448300
GeneDB PCHAS_1448300
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000455.01.0, PC001264.02.0, PC400421.00.0, PCHAS_144830
Orthologs PBANKA_1446100 , PF3D7_1231400 , PKNH_1450800 , PVP01_1449600 , PVX_100515 , PY17X_1448600
Google Scholar Search for all mentions of this gene