(C) and confocal and (D) localization of PfGSK3-GFP in late trophozoites (LT) schizonts (S) and merozoites (M) revealed perinuclear and cytosolic distribution. Nuclei are stained with DAPI (blue). localization studies indicate that the kinase localizes in nuclear or perinuclear compartments as well as in the cytosol in erythrocytic stages of the parasite.Prinz B, Harvey KL, Wilcke L, Ruch U, Engelberg K, Biller L, Lucet I, Erkelenz S, Heincke D, Spielmann T, Doerig C, Kunick C, Crabb BS, Gilson PR, Gilberger TW. Hierarchical phosphorylation of apical membrane antigen 1 is required for efficient red blood cell invasion by malaria parasites. Sci Rep. 2016 6:34479.