Species | Disruptability | Reference | Submitter | |
---|---|---|---|---|
P. berghei ANKA |
Refractory |
RMgm-242 | Imported from RMgmDB | |
P. falciparum 3D7 |
Possible |
http://wiredspace.wits.ac.za/handle/10539/12599 | Theo Sanderson, Wellcome Trust Sanger Institute | |
P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
P. falciparum 3D7 |
Possible |
19040641 \"Deletion of this gene from P. falciparum had no effect on asexual parasite growth, but surprisingly also had no effect on gametocyte development or exflagellation, suggesting that these life cycle stages do not utilize host-derived glycerol as a carbon source. \" |
Theo Sanderson, Francis Crick Institute | |
P. falciparum 3D7 |
Possible |
23954205 \"Disruption of the P. falciparum glycerol kinase gene produced viable parasites, but their growth was significantly reduced to 56.5±1.8% when compared to wild type parasites. (14)C-glycerol incorporation into the major phospholipids of the parasite membrane, phosphatidylcholine and phosphatidylethanolamine, was 48.4±10.8% and 53.1±5.7% relative to an equivalent number of wild type parasites.\" |
Theo Sanderson, Francis Crick Institute |
Species | Stage | Phenotype | Reference | Submitter |
---|---|---|---|---|
P. falciparum 3D7 | Asexual |
Attenuated |
http://wiredspace.wits.ac.za/handle/10539/12599 | Theo Sanderson, Wellcome Trust Sanger Institute |
P. falciparum 3D7 | Asexual |
No difference |
19040641 \"Deletion of this gene from P. falciparum had no effect on asexual parasite growth, but surprisingly also had no effect on gametocyte development or exflagellation, suggesting that these life cycle stages do not utilize host-derived glycerol as a carbon source. \" |
Theo Sanderson, Francis Crick Institute |
P. falciparum 3D7 | Asexual |
Attenuated |
23954205 \"Disruption of the P. falciparum glycerol kinase gene produced viable parasites, but their growth was significantly reduced to 56.5±1.8% when compared to wild type parasites. (14)C-glycerol incorporation into the major phospholipids of the parasite membrane, phosphatidylcholine and phosphatidylethanolamine, was 48.4±10.8% and 53.1±5.7% relative to an equivalent number of wild type parasites.\" |
Theo Sanderson, Francis Crick Institute |
P. falciparum 3D7 | Gametocyte |
No difference |
19040641 \"Deletion of this gene from P. falciparum had no effect on asexual parasite growth, but surprisingly also had no effect on gametocyte development or exflagellation, suggesting that these life cycle stages do not utilize host-derived glycerol as a carbon source. \" |
Theo Sanderson, Francis Crick Institute |
PlasmoDB | PCHAS_1368900 |
GeneDB | PCHAS_1368900 |
Malaria Metabolic Pathways | Localisation images Pathways mapped to |
Previous ID(s) | PC001056.02.0, PCAS_136890, PCHAS_136890 |
Orthologs | PBANKA_1364300 , PF3D7_1351600 , PKNH_1249400 , PVP01_1203200 , PVX_083470 , PY17X_1370100 |
Google Scholar | Search for all mentions of this gene |