| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Refractory |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Refractory |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. falciparum 3D7 | Asexual |
Refractory |
36511651 (Knock down)
\". GlmS-ribozyme mediated inducible knockdown (iKD) showed its 15 indispensability for the asexual blood stages of the parasite. The protein was found to be 16 associated with ER, and its inducible knockdown disrupted ER morphology and 17 development . Further, the iKD of PfUSP increased DHA sensitivity and polyubiquitination of 18 specific parasite proteins, suggesting its role in protein homeostasis and drug-induced stress 19 tolerance. T\" |
Theo Sanderson, Francis Crick Institute |
| PlasmoDB | PCHAS_1002000 |
| GeneDB | PCHAS_1002000 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PC300262.00.0, PCAS_100100, PCHAS_100200 |
| Orthologs | PBANKA_1001100 , PF3D7_0403500 , PKNH_0301300 , PVP01_0302700 , PVX_001075 , PY17X_1002500 |
| Google Scholar | Search for all mentions of this gene |