Normal numbers of gametes and ookinetes are produced. G2-KO ookinetes show aberrant morphology. G2-KO ookinetes were typically wider and shorter and possessed a bulging area near the central part of the cell. G2-KO parasite-infected mosquitoes formed oocysts that developed normally (although in reduced numbers) and formed large numbers of sporozoites. However, the sporozoites were also of abnormal shape being shorter and possessing an enlarged, bulging area typically near the middle or posterior end of the cell. Sporozoites did not invade salivary glands.

Normal numbers of gametes and ookinetes are produced. G2-KO ookinetes show aberrant morphology. G2-KO ookinetes were typically wider and shorter and possessed a bulging area near the central part of the cell. G2-KO parasite-infected mosquitoes formed oocysts that developed normally (although in reduced numbers) and formed large numbers of sporozoites. However, the sporozoites were also of abnormal shape being shorter and possessing an enlarged, bulging area typically near the middle or posterior end of the cell. Sporozoites did not invade salivary glands.

Sporozoites did not invade salivary glands and transmission to mice by mosquito bite did not occur. Infection of mice by intravenous inoculation of mutant sporozoites has not been reported.