Species | Disruptability | Reference | Submitter | |
---|---|---|---|---|
P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
P. falciparum 3D7 |
Possible |
36400305 \"We show using C-terminal truncations and gene knockouts of each of Pfczif1 and Pfczif2 that neither are essential for blood stage growth. However, they could not both be knocked out simultaneously, suggesting that at least one is needed for parasite growth in vitro. Immunofluorescence localisation of PfCZIF1 and PfCZIF2 indicated that both proteins occur in discrete foci on the periphery of the parasite\'s cytosol and biochemical assays suggest they are peripherally associated to a membrane. \" |
Theo Sanderson, Francis Crick Institute |
Species | Stage | Phenotype | Reference | Submitter |
---|---|---|---|---|
P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
P. falciparum 3D7 | Asexual |
Possible |
36400305 \"We show using C-terminal truncations and gene knockouts of each of Pfczif1 and Pfczif2 that neither are essential for blood stage growth. However, they could not both be knocked out simultaneously, suggesting that at least one is needed for parasite growth in vitro. Immunofluorescence localisation of PfCZIF1 and PfCZIF2 indicated that both proteins occur in discrete foci on the periphery of the parasite\'s cytosol and biochemical assays suggest they are peripherally associated to a membrane. \" |
Theo Sanderson, Francis Crick Institute |
PlasmoDB | PCHAS_0721800 |
GeneDB | PCHAS_0721800 |
Malaria Metabolic Pathways | Localisation images Pathways mapped to |
Previous ID(s) | PC000126.04.0, PC000256.03.0, PC000432.03.0, PCHAS_072180 |
Orthologs | PBANKA_0712700 , PF3D7_0818100 , PKNH_0501900 , PVP01_0517200 , PVX_089510 , PY17X_0712900 |
Google Scholar | Search for all mentions of this gene |