The generation of mutants with a disrupted gene indicate a non-essential role during asexual blood stage growth/multiplication.The gene deletion mutant has not been cloned and the phenotype of the gene deletion mutant has not been not analysed in detail (the growth rate has not been determined).

dhhc10;lap2::gfp parasites showed LAP2::GFP-positive female gametocytes with protein dispersed throughout the cytoplasm, as described previously.

Analyses of the dhhc10;lap2::gfp ookinetes showed diffuse localisation of LAP2::GFP in the cytoplasm ookinetes. LAP2 has previously been localized to the ookinete crystalloids by both live fluorescence imaging and immunoelectron microscopy. The cytoplasmic location of LAP2::GFP and absence of 'focal' localisation in crystalloids confirms the absence of crystalloid formation in mutants lacking expression of DHHC10

Normal numbers of gametocytes are produced. Normal fertilisation rate and ookinete production. Ookinetes however lack crystalloids (crystalloid body; crystalloid organelle).

Normal numbers of gametocytes are produced. Normal fertilisation rate and ookinete production. Ookinetes however lack crystalloids (crystalloid body; crystalloid organelle).

Normal numbers of oocysts are produced. However, oocysts fail to produce sporozoites

Normal numbers of oocysts are produced. However, oocysts fail to produce sporozoites

No sporozoites are formed

No sporozoites are formed