Last updated 4 years ago

Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-4115 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-792 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. yoelii yoelii 17X
Refractory
RMgm-4383 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-4115 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-792 Imported from RMgmDB
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
No difference
RMgm-4115 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-792 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-4115 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-792 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-4115 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-792 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-4115 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-792 Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-4115
Normal sporozoite formation. Sporozoites fail to infect mice (parasites arrest during liver stage development; see 'Additional remarks phenotypes').
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-792
Normal sporozoite production. Gliding motility, cell traversal and hepatocyte invasion of sporozoites is normal. Infectivity of sporozoites in vivo is 10.000 lower compared to wild type sporozoites (as measured by prepatent period). Development of liver stages is affected (see 'Additional remarks phenotype').
Imported from RMgmDB

More information

PlasmoDB PCHAS_0212800
GeneDB PCHAS_0212800
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000723.01.0, PC107933.00.0, PC301284.00.0, PCAS_021280, PCHAS_021280
Orthologs PBANKA_0214400 , PF3D7_0730300 , PKNH_0215200 , PVP01_0216000 , PVX_081810 , PY17X_0215800
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