| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
RMgm-835 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| P. falciparum 3D7 |
Possible |
34724812 Although no growth defect on parasite proliferation was observed, Pf-DNMT2KO parasites showed a selective downregulation of proteins with a GAC codon bias. This resulted in a significant shift in parasite metabolism, priming KO parasites for being more sensitive to various types of stress. |
Theo Sanderson, Francis Crick Institute | |
| P. falciparum 3D7 |
Possible |
37026483 \"PfDNMT2 disruption led to an increased proliferation phenotype, with the parasites having an extended schizont stage and producing a higher number of progenies.\" |
Theo Sanderson, Francis Crick Institute | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
RMgm-835 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. falciparum 3D7 | Asexual |
Difference from wild-type |
34724812 Although no growth defect on parasite proliferation was observed, Pf-DNMT2KO parasites showed a selective downregulation of proteins with a GAC codon bias. This resulted in a significant shift in parasite metabolism, priming KO parasites for being more sensitive to various types of stress. |
Theo Sanderson, Francis Crick Institute |
| P. falciparum 3D7 | Asexual |
Possible |
37026483 \"PfDNMT2 disruption led to an increased proliferation phenotype, with the parasites having an extended schizont stage and producing a higher number of progenies.\" |
Theo Sanderson, Francis Crick Institute |
| PlasmoDB | PCHAS_0209800 |
| GeneDB | PCHAS_0209800 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PC000283.02.0, PC000892.01.0, PCAS_020980, PCHAS_020980 |
| Orthologs | PBANKA_0211400 , PF3D7_0727300 , PKNH_0211900 , PVP01_0213000 , PVX_081670 , PY17X_0212800 |
| Google Scholar | Search for all mentions of this gene |