Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-4130 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-1371 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-629 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-626 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-4329 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-4130 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-1371 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-629 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-626 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
Difference from wild-type
RMgm-4329
Not essential for blood stage growth/multiplication
Imported from RMgmDB
P. falciparum 3D7 Asexual
No difference
34756057 (Knock down) Theo Sanderson, Francis Crick Institute
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-4130
Strongly reduced formation of male gametes
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-1371
Strongly reduced exflagellation
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-629
Strongly reduced gametocyte production. The few gametocytes present show an aberrant morphology. These aberrant forms are unable to fertilize and produce ookinetes
Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-626
Strongly reduced gametocyte production. The few gametocytes present show an aberrant morphology. These aberrant forms are unable to fertilize and produce ookinetes
Imported from RMgmDB
P. falciparum 3D7 Gametocyte
No difference
34756057 (Knock down) Theo Sanderson, Francis Crick Institute
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-629
No ookinete production
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-626
No ookinete production
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-626
No ookinete and oocyst production
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-629
No ookinete and oocyst production
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-1371
No sporozoites in vivo
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-626
No ookinete, oocyst and sporozoite production
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-629
No ookinete, oocyst and sporozoite production
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-1371
No transmission by bite of infected mosquitoes
Imported from RMgmDB

More information

PlasmoDB PCHAS_0206700
GeneDB PCHAS_0206700
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000221.05.0, PC302103.00.0, PCAS_020670, PCHAS_020670
Orthologs PBANKA_0208300 , PF3D7_0104800 , PKNH_0208700 , PVP01_0209900 , PVX_081515 , PY17X_0209700
Google Scholar Search for all mentions of this gene