| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
RMgm-4481 | Imported from RMgmDB | |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
Difference from wild-type |
RMgm-4481
Parasites lacking PbmaLS_05 showed a decreased ability to infect RBC (and immature reticulocytes), resulting in reduced peripheral parasite loads. Reduced mortality due to experimental cerebral malaria (ECM). None of the mice infected with mutant sporozoites developed ECM; in contrast, mice infected with WT sporozoites, displayed signs of ECM between day 7 and 9 p.i. Mice die from high parasitemia and anemia. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-4481
No data provided. Assuming normal sporozoite production. |
Imported from RMgmDB |
| PlasmoDB | PBANKA_1401000 |
| GeneDB | PBANKA_1401000 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | PB000437.03.0, PB000574.01.0, PB000860.00.0, PB001033.03.0, PBANKA_140100 |
| Orthologs | PCHAS_1402900 , PF3D7_1302500 , PKNH_1402700 , PVP01_1403400 , PVX_121965 , PY17X_1402600 |
| Google Scholar | Search for all mentions of this gene |