Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Refractory
35277503 (Knock down)
\"In this study, we use inducible knockdown studies in the human malaria parasite, Plasmodium falciparum, to show that two RAP proteins, PF3D7_0105200 (PfRAP01) and PF3D7_1470600 (PfRAP21), are essential for parasite survival and localize to the mitochondrion. Using transcriptomics, metabolomics, and proteomics profiling experiments, we further demonstrate that these RAP proteins are involved in mitochondrial RNA metabolism.\"
Theo Sanderson, Francis Crick Institute

More information

PlasmoDB PBANKA_1333800
GeneDB PBANKA_1333800
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000874.01.0, PBANKA_133380
Orthologs PCHAS_1338400 , PF3D7_1470600 , PKNH_1210400 , PVP01_1236200 , PVX_116940 , PY17X_1338500
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