| Species | Disruptability | Reference | Submitter | |
|---|---|---|---|---|
| P. berghei ANKA |
Possible |
RMgm-328 | Imported from RMgmDB | |
| P. berghei ANKA |
Possible |
PlasmoGEM (Barseq) | PlasmoGEM | |
| P. falciparum 3D7 |
Possible |
USF piggyBac screen (Insert. mut.) | USF PiggyBac Screen | |
| Species | Stage | Phenotype | Reference | Submitter |
|---|---|---|---|---|
| P. berghei ANKA | Asexual |
No difference |
RMgm-328 | Imported from RMgmDB |
| P. berghei ANKA | Asexual |
No difference |
PlasmoGEM (Barseq) | PlasmoGEM |
| P. berghei ANKA | Gametocyte |
No difference |
RMgm-328 | Imported from RMgmDB |
| P. berghei ANKA | Ookinete |
Difference from wild-type |
RMgm-328
Normal rate of fertilization and ookinete production. Ookinetes showed reduced motility. Mutant ookinetes showed an average speed of 3.7 m/min and wild type ookinetes an average speed of 6.5 m/min. Mutant ookinetes transiently showed fast locomotion comparable to wild type. |
Imported from RMgmDB |
| P. berghei ANKA | Oocyst |
Difference from wild-type |
RMgm-328
Strongly reduced oocyst formation in Anopheles stephensi mosquitoes, both after feeding mosquitoes on infected mice and by membrane feeding of in vitro cultured mature ookinetes to mosquitoes. The oocysts formed, produced normal numbers of sporozoites. |
Imported from RMgmDB |
| P. berghei ANKA | Sporozoite |
Difference from wild-type |
RMgm-328
Sporozoites have lost the ability to invade salivary glands. Midgut-associated sporozoites were non-infectious to mice after intravenous injection. Sporozoites showed strongly reduced motility and never displayed productive (forward) locomotion. |
Imported from RMgmDB |
| P. berghei ANKA | Liver |
Difference from wild-type |
RMgm-328
Midgut-associated sporozoites were non-infectious to mice after intravenous injection. |
Imported from RMgmDB |
| PlasmoDB | PBANKA_1232400 |
| GeneDB | PBANKA_1232400 |
| Malaria Metabolic Pathways | Localisation images Pathways mapped to |
| Previous ID(s) | CPbeta, PB000641.00.0, PBANKA_123240 |
| Orthologs | PCHAS_1233000 , PF3D7_0517600 , PKNH_1015700 , PVP01_1016400 , PVX_080370 , PY17X_1235800 |
| Google Scholar | Search for all mentions of this gene |