Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. falciparum 3D7 Asexual
Attenuated
34766750 (Knock down)
\"The knockdown of PfACS or its inhibition resulted in impaired parasite growth. Decreased levels of PfACS also led to differential histone acetylation patterns, altered variant gene expression, and concomitantly decreased cytoadherence of infected red blood cells containing knocked-down parasites. \"
Theo Sanderson, Francis Crick Institute

More information

PlasmoDB PBANKA_1126500
GeneDB PBANKA_1126500
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000459.03.0, PBANKA_112650
Orthologs PCHAS_1126000 , PF3D7_0627800 , PKNH_1122000 , PVP01_1121700 , PVX_114495 , PY17X_1128000
Google Scholar Search for all mentions of this gene